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ADPN modulates fibrosis by inhibiting HSC activation, proliferation and migration, and ECM remodeling, while improving hepatic function, while improving hepatic function.
Undiagnosed diabetes and prediabetes are common among trauma patients and increase perioperative complication rates, yet routine glycemic screening at hospital admission is rarely performed. We compared 10 supervised machine learning (ML) algorithms for early detection of impaired glucose metabolism in 1789 trauma surg...
This review summarizes the principal epigenetic changes involved in HSC activation, initiation/progression of liver fibrosis, and discusses recent interventions designed to modulate these epigenetic changes.
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