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Sep 2026

Cocaine disrupts stress resilience through state-dependent dopaminergic mechanisms in the nucleus accumbens.

BACKGROUND Depression and substance use disorders frequently co-occur, yet it remains unclear whether similar depression-related behaviors reflect a common underlying neural state. Cocaine use is associated with worsening depressive symptoms, suggesting that drug exposure may interact with pre-existing behavioral state...

Yoko H. Ohnishi, Yoshinori N. Ohnishi, Y. Kawahara et al. · 0 citations

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