Review
Open access
Jul 2026
The expanding landscape of Deltex: signaling crosstalk and clinical implications.
The deltex (DTX) gene family encodes RING-type E3 ubiquitin ligases that are central to the regulation of the Notch signaling pathway, a mechanism governing cell fate, differentiation, proliferation, and apoptosis during development and adult tissue homeostasis. In Drosophila melanogaster, the Deltex (Dx) fine-tunes No...
Vartika Sharma, Pratikshya Sahoo, M. Mutsuddi et al.
· Cellular and Molecular Life... · 0 citations