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A. Mrestani

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Case report Open access Sep 2026

Tenofovir in Progressive Multifocal Leukoencephalopathy

Objectives Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal demyelinating disease of the CNS caused by reactivation of the JC polyomavirus (JCV), typically in immunocompromised individuals. As no specific therapy against JCV exists, current management focuses on immune reconstitution. Recently, a...

J. Lier, A. Mrestani, Max Braune et al. · 0 citations

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