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A. Montero-Calle

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Open access Aug 2026

Comparative proteomic analysis of the angiogenic response in an in vitro model of vascular endothelial cells to excretory/secretory and somatic antigens of Dirofilaria immitis

Dirofilaria immitis infection induces endothelial inflammation and vascular remodeling, contributing to heartworm disease pathology. While excretory/secretory antigens (DiES) are known to promote angiogenesis, somatic antigens (DiSA) exhibit different modulatory effects. This study aims to characterize the differential...

Manuel Collado-Cuadrado, Alfonso Balmori-de la Puente, A. Montero-Calle et al. · 0 citations
Open access Aug 2026

Mapping the Human Ghost Proteome: Classification and Experimental Detection Biases in the Identification of Alternative Microproteins

The discovery of alternative proteins (AltProts), translated from non-canonical ORFs, has expanded the human proteome and revealed a hidden layer known as the “ghost proteome”. Despite increasing evidence, AltProts detection remains challenging due to their small size, physicochemical heterogeneity, and lack of annotat...

A. Montero-Calle, A. Peláez-García, A. J. Martín-Galiano et al. · 0 citations

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