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Author

Á. Molina

2 papers indexed here

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Aug 2026

Antibody-Drug Conjugates Synergize with Agonist Anti-CD137 Monoclonal Antibodies in Solid Tumors.

Antibody-drug conjugates (ADCs) show clinical efficacy against several solid malignancies, inducing cytotoxic effects in malignant cells accompanied by changes in the composition of the tumor stroma. The therapeutic effects of some ADCs have been shown to be potentiated by combination with anti-PD(L)1 checkpoint inhibi...

Gabriel Gomis, Claudia Herrero, Saioa Arrieta-Aranzueque et al. · 1 citation
Open access Sep 2026

TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

This study provides evidence for a key role of TNFR1, as expressed by malignant cells, in orchestrating a pro-tumor immunosuppressive environment through secondary inflammatory mediators. Results highlight the relevance of interfering TNFα/TNFR1 in cancer immunotherapy.

Elixabet Bolaños, Lorena Cañas-Zabala, Irene Olivera et al. · 0 citations

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