Redox biology represents a universal molecular language that encodes biochemical gradients, distinguishing healthy from diseased tissues with significant precision. The convergence of redox signaling and peptide self-assembly results in a versatile chemical framework for next-generation theranostics. Peptides, programm...
Soheil Haddadzadegan, Cong-Xi Huang, M. Ghafouri et al.· Advanced Drug Delivery Revie...· 0 citations
Protease-recognition motifs require reevaluation within dense-phase architectures to enable efficient intracellular cargo release through coacervate disassembly within phase-separating peptides.
Pooja Sharma, Soheil Haddadzadegan, M. Ghafouri et al.· ACS Nano· 0 citations
It is demonstrated that single-molecule mass measurements with mass photometry can capture RNA-protein interactions in phase-separated protein systems and can distinguish between charge neutralization, which drives coacervation, and complex formation, which mediates phase re-entry, making it a highly complementary tool...
Axel Leppert, Jesper Shiapan, Irena Papageorgiou et al.· bioRxiv· 0 citations
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