Abstract Background Burn injuries affect the central nervous system, and evidence suggests they induce changes in cortical excitability related to motor dysfunction. The current study investigated markers of neuroplasticity in the motor cortex and motor performance in the subacute period following burn injury. Methods...
Grant Rowe, Mark W. Fear, D. Edgar et al.· Burns & Trauma· 0 citations
Clinical meaningful improvements were observed, with the PGx-Guided group showing greater reductions in depressive symptom severity, higher rates of treatment response and remission, and improved quality-of-life outcomes compared with TAU.
B. Roberts, Z. Cooper, A. Miljevic et al.· Translational Psychiatry· 0 citations
The results indicate that TRD does not represent a single, unified PGx-predicted 'poor pharmacological responder' phenotype but instead reflects a biologically heterogeneous collection of distinct PGx profiles, and actionable PGx phenotypes are neither enriched in TRD nor associated with greater TRD severity.
B. Roberts, A. Miljevic, Lauren A. Hennessy et al.· Pharmacogenetics & Genomics· 0 citations
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