A red onion peel-derived PPARγ inhibitor suppresses BPA-induced DNA synthesis and lipid accumulation in mesenchymal stem cells and mesenchymal-rich cancer cells.
This study examined obesity- and insulin-associated gene expression, newly synthesised DNA (a measure of survival following mitosis), lipid accumulation (integral to cell differentiation), and chronic inflammatory soluble factors, including transforming growth factor β (TGFβ), interleukin-6 (IL-6), and chemokine CC-mot...