Author

A. Merits

2 papers indexed here

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Open access Sep 2026

Tuning intracellular immunity by Nodamura virus B2 protein enhances self-amplifying RNA activity

Self-amplifying RNA (saRNA) offers a powerful approach for vaccine development, as its replicative nature within cells provides prolonged antigen expression together with self-adjuvanticity. However, its potency is often limited by innate immune responses, particularly those triggered by intracellular double-stranded R...

R. Y. Sanchez-David, Josephine Nemegeer, Hoang Duy Le et al. · Nature Communications · 0 citations

Open access Aug 2026

Pyridin-3-carbohydrazide strongly impairs Mayaro and Chikungunya virus replication in vitro

The data suggest that P-3-C exhibits a potential multitarget mechanism of action and highlight its antiviral activity against different alphavirus strains; however, this efficacy could be dependent on the cell line used.

N. Contreras, N. Cassani, Mikaela dos Santos Marinho et al. · Archives of Virology · 0 citations