Author

A. Meden

2 papers indexed here

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Open access Oct 2026

Novel NIR DDNP-type solvatochromic and fluorogenic probes for amyloid β detection.

Selective near-infrared fluorescent probes for amyloid β aggregates are of considerable interest as molecular imaging tools for the diagnosis and study of Alzheimer's disease. Herein, we describe the rational design and synthesis of DDNP-type donor-π-acceptor fluorophores incorporating a fixed N,N-dimethylamino donor g...

Matic Rogan, L. Blinc, Luka Rejc et al. · Bioorganic chemistry (Print) · 0 citations

Open access Oct 2026

Synthesis of 3-Amino-4-(Hydroxymethyl)-β-Lactam Branch Point and Its Late-Stage C4 Functionalization with Ceftaroline-Sidechain Monobactams and Their Biological Evaluation

Two alternative routes to 3-amino-4-(hydroxymethyl)-2-azetidinone are compared, a synthon carrying handles at N1, C3 and C4, starting from ethyl glyoxylate and from (R)-glyceraldehyde acetonide, which replaces a low-yielding NaBH4 ester reduction with a near-quantitative oxidative cleavage/reduction sequence.

Vid Kavaš, Majda Golob, A. Meden et al. · Molecules · 0 citations