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Review Open access Oct 2026

Pancreatic acinar cell carcinoma demonstrates marked clinical heterogeneity and recurrent actionable genomic alterations

Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with a molecular profile distinct from pancreatic ductal adenocarcinoma (PDAC) but is commonly treated using extrapolated paradigms. We retrospectively identified patients with histologically confirmed PACC at a tertiary academic center...

Noor Farhoud, R. Al-Rajabi, J. Baranda et al. · 0 citations
Open access Oct 2026

Outcomes following biliary decompression interventions for jaundiced patients with malignant intrahepatic obstruction from metastatic cancer.

293 Background: Hyperbilirubinemia due to malignant intrahepatic biliary obstruction frequently limits eligibility for systemic therapy. Intrahepatic biliary drainage interventions (IBDI), including endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic biliary drainage (PTBD), are...

Tessa Crilley, Adeel Arshad, Mitchell L. Ramsey et al. · 0 citations

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