SULFORAPHANE SUPPRESSES HEPATOCELLULAR CARCINOMA IN MICE VIA ACTIVATING p53, MITIGATING OXIDATIVE STRESS, AND INHIBITING ANGIOGENESIS.
BACKGROUND Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Sulforaphane (SF) is a natural isothiocyanate that exhibits anticarcinogenic activity against various cancer cells in vivo and in vitro, with no observed side effects. It also has a prophylactic effect against early stages of some ca...