Open access
Sep 2026
TANGO6 coordinates transcription and translation through nucleocytoplasmic partitioning
Coordinated RNA and protein synthesis is fundamental to cell function and survival. Here, we show that TANGO6, a nucleocytoplasmic RNA binding protein, is an integral component of the proteostasis control axis, regulating both transcription and translation. In the nucleus, TANGO6 is recruited to gene promoters alongsid...
Gonzalo Bigliani, C. Ballaré, José Wojnacki et al.
· Science Advances · 0 citations