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Author

A. Luikku

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2 papers indexed here

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Open access Oct 2026

The Kuopio Idiopathic Normal Pressure Hydrocephalus Protocol Revisited: The Predictive Value of Cerebrospinal Fluid Tap Test.

BACKGROUND AND OBJECTIVES Idiopathic normal pressure hydrocephalus is a condition with gait impairment, incontinence, and cognitive decline, treated with shunt surgery. The Gothenburg scale (GBS) provides comprehensive assessment of symptoms and outcomes. The cerebrospinal fluid tap test (CSF-TT) is used as a prognosti...

A. Luikku, Henna-Kaisa Jyrkkänen, N. Danner et al. · 0 citations
Review Open access Aug 2026

Live brain biopsy during CSF shunt surgery for precision diagnostics and multi-omic research

Diagnostic testing and neurosurgical management involving CSF shunting in patients with idiopathic normal pressure hydrocephalus (iNPH) offers a unique, ethically sustainable opportunity to study the aging human brain. The common co-occurrence of neurodegenerative pathologies such as amyloid-β plaques and neurofibril...

Heikki E. M. Lukkarinen, A. Luikku, Antonios Dougalis et al. · 0 citations

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