Open access
Sep 2026
Proteomic-guided targeted treatment of leukoencephalopathy with calcification and cysts.
Precision therapeutic approaches for rare neurological diseases are often hampered by a limited molecular understanding of the disease. Here, we report the first application of spatially-resolved proteomics to guide targeted treatment in a monogenic leukoencephalopathy. We investigated leukoencephalopathy with calcific...
Nils Briel, A. Köpp, Hanna Meister et al.
· Brain : a journal of neurolo... · 0 citations