Author

A. Klawonn

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Open access Jul 2026

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Treatment application of Pep19‐2.5 via the nasal aerosol route reduces IL‐1β levels, eosinophil infiltration in bronchoalveolar lavage and significantly improved lung function in an in vivo HDM‐mouse model of allergic airway inflammation.

Jonas Engelhardt, Nico Kirsch, Aileen Kerfin et al. · Advancement of science · 0 citations

Open access Jul 2026

Base editing-derived models of human WDR34 and WDR60 disease alleles replicate retrograde intraflagellar transport (IFT) and hedgehog signaling defects

Base editing derived cell models shed light on the role of ciliary dynein complex components for intraflagellar transport, hedgehog signaling and differential regulation of genes associated with Golgi intracellular transport using human disease alleles.

Dinu Antony, Elif Yilmaz Güleç, A. Klawonn et al. · Communications Biology · 0 citations