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A. Kinnunen

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Review Open access Aug 2026

Genetic associations with EEG signatures in mild cognitive impairment: insights into Alzheimer's disease pathophysiology

The convergence of candidate genes on synaptic, neurodevelopmental and neuroinflammatory pathways, and genetically informed clustering linked to plasma p-tau217 and delayed verbal recall, supports the use of EEG-derived endophenotypes for dissecting heterogeneity in early cognitive decline and AD-related pathology.

A. Siitonen, T. Saarinen, M. Liljestrom et al. · 0 citations
Open access Aug 2026

Cognitive components derived from traditional neuropsychological tests and their associations with plasma p-tau217 and p-tau181 in mild cognitive impairment: a multisite analysis.

The findings indicate that a robust four-factor cognitive structure can be identified in clinically defined MCI cohorts without prior biological selection, and the association between latent memory factors and plasma p-tau217, observed primarily in cohorts with higher biomarker burden or clearer amnestic profiles, high...

Ana S. Perez, Hugo L. Hammer, V. Andersson et al. · 0 citations

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