Open access
Jul 2026
Characterizing the Roles of Dysferlin Deficiency in Function, Polarization, and Secretome of Human iPSC-Derived Macrophages 2251399
Dysferlin loss in iMPs results in cell-autonomously altered transcriptome, secretome, and endocytic function, which may contribute to LGMDR2 muscle pathology and disease progression.
Amber Detwiler, Rachel Luner, Alex Schneider et al.
· Journal of Immunology · 0 citations