Ambroxol in Gaucher disease and GBA1-related Parkinson disease: an updated systematic review.
BACKGROUND Ambroxol (ABX) is a central nervous system (CNS)-penetrant compound that can increase glucocerebrosidase activity and has been investigated in Gaucher disease (GD) and GBA1-related Parkinson disease (GBA1-PD). METHODS This PRISMA 2020 systematic review and narrative synthesis searched PubMed/MEDLINE, Europ...