Multi-ancestry MHC-pQTL mapping reveals disease-linked HLA protein networks and shared genetic architecture
The major histocompatibility complex (MHC) is one of the most polymorphic and disease-relevant regions of the human genome, yet the downstream effects of MHC variation on circulating protein networks across ancestries remain incompletely defined. Here, we conducted multi-ancestry protein quantitative trait locus (pQTL)...