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Author

A. Ielo

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Open access Oct 2026

Wearable Inertial Phenotyping of Freezing of Gait in Parkinson’s Disease: Biomechanical Signatures, Subject-Independent Classification, and Clinical Associations

Freezing of gait (FoG) in Parkinson’s disease is clinically heterogeneous, yet wearable-sensor studies predominantly focus on binary FoG detection. We investigated whether right-ankle inertial signals can characterize clinically meaningful FoG manifestations within a three-stage conditional framework. Accelerometer and...

A. Ielo, L. Bonanno, A. Quartarone et al. · 0 citations
Open access Oct 2026

Characterizing single-shell NODDI-DTI estimates through associations with plasma biomarkers and cognitive performance

White matter (WM) degeneration is an important feature of aging and Alzheimer’s disease (AD). Neurite orientation dispersion and density imaging derived from diffusion tensor imaging (NODDI-DTI) is a technique that allows the estimation of neurite density index (NDI) and orientation dispersion index (ODI) in WM fro...

Giovanni Restuccia, A. Ielo, V. L. Buono et al. · 0 citations

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