Author

A. Iafrate

3 papers indexed here

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Sep 2026

Comparative Transcriptomic and Immune Profiling Reveals a Shared Molecular Identity Between Clear Cell Odontogenic Carcinoma and Hyalinizing Clear Cell Carcinoma.

Clear cell odontogenic carcinoma (CCOC) and hyalinizing clear cell carcinoma (HCCC), rare head-and-neck malignancies with recurrent EWSR1::CREB family fusions, show overlapping morphologic and immunophenotypic features; no standardized systemic therapy for either exists. Given tissue constraints, the molecular relation...

Helen X. Hou, An-Nie Li, Bidish Kumar Patel et al. · Molecular Cancer Research · 0 citations

Jul 2026

Systematic Targeting of Protein Complexes with Molecular COUPLrs

Small molecules that modulate protein complexes have transformed cell biology and oncology, yet few chemical starting points exist to probe protein-protein interactions. To expand this space, we developed molecular COUPLrs, elaborated small molecules flanked by two cysteine-reactive warheads. Using CONNECT, an integrat...

Diane Yang, S. Harry, H. Chong et al. · Cancer Discovery · 0 citations

Open access Aug 2026

Associations of Age With Tumor Genomic Characteristics in Relapsed/Refractory Cancers Interrogated With the NCI-MATCH Trial Targeted Gene Panel Assay

Comparing AYAs with non-AYAs among patients having relapsed/refractory disease, no significant differences in SNV/indel prevalence were observed, but CCND1 amplifications were more prevalent in AYA breast cancer.

Hari Sankaran, Y. Kotliarov, Ying-Dong Zhao et al. · JCO Precision Oncology · 0 citations