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Author

A. Hulshof

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2 papers indexed here

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Open access Sep 2026

Endotheliopathy and VWF-ADAMTS13 axis dysfunction in VEXAS thrombogenicity.

Markedly increased risk of thrombosis has been described as a key clinical feature of the recently described VEXAS (vacuoles, E1 enzyme, X linked, autoinflammatory, somatic) syndrome. Critically however, the pathological mechanisms underlying VEXAS-associated hypercoagulability remain poorly understood. We addressed th...

A. Hulshof, E. Groarke, S. Schneppenheim et al. · 0 citations
Review Open access Aug 2026

Whole genome sequencing to elucidate novel genetic modifiers of FVIII clearance.

Despite significant insights into factor VIII (FVIII) biosynthesis, the mechanisms involved in FVIII clearance remain poorly defined. To investigate genetic modifiers of FVIII clearance, we studied 106 SNPs across 43 different loci previously reported to influence plasma FVIII and/or von Willebrand (VWF) levels and rev...

A. Hulshof, Lilian Antunes Heck, F. Atiq et al. · 0 citations

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