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Sep 2026

Abstract A002: Epigenetic Regulation of the GDF15 Immune Checkpoint Determines Sensitivity of Atypical Teratoid/Rhabdoid Tumors to Natural Killer Cell Immunotherapy

Atypical teratoid/rhabdoid tumors (ATRTs) are highly aggressive pediatric central nervous system malignancies characterized by poor clinical outcomes despite intensive multimodal therapy, including surgery, chemotherapy, and radiation. Although molecular classification has improved our understanding of ATRT biology,...

V. Gopalakrishnan, Jyothishmathi Swaminathan, Ben Ho et al. · 0 citations
Sep 2026

Abstract PR013: Childhood Cancer Data Initiative’s Research Characterization Data Reveals Novel Biology

The Childhood Cancer Data Initiative (CCDI), a 10-year $50M per year data initiative, brings together doctors, researchers, and families affected by cancer to learn from every child diagnosed with cancer, speeding discovery for new medical advances. In partnership with the Children’s Oncology Group (COG), NCI launche...

Emily S. Boja, Subhashini Jagu, Joseph A. Flores-Toro et al. · 0 citations

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