BACKGROUND
Oligodendroglioma is a primary central nervous system tumor classified by the presence of isocitrate dehydrogenase (IDH) mutations and codeletion of 1p/19q. A lack of faithful preclinical model systems for this disease has limited progress in understanding the biology of this genetically unique subtype of ad...
Ipsita G. Kundu, Nicolas Toro, Aaron Y. Mochizuki et al.· Neuro-Oncology· 0 citations
Spatial-ATAC-Hi-C enables the profiling of both chromatin accessibility and organization in a spatially resolved manner, as demonstrated on mouse brain and human glioblastoma and astrocytoma samples.
Ping Wang, Juan Wang, Qi-Xuan Wang et al.· Nature Methods· 0 citations
The hallmarks of cancer is used as an organizing framework to synthesize preclinical, translational, and clinical evidence on chemokine circuits in glioblastoma and evaluated recurrent mechanistic pathways, distinguished causal functions from context-dependent biomarker associations, and assessed their therapeutic rele...
Rafal Chojak, Jillyn R. Turunen, Noah B. Drewes et al.· Journal of Neuro-Oncology· 0 citations
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