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A. Hedström

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Open access Sep 2026

Genetic modification of obesity-associated disability progression in multiple sclerosis

Obesity has been associated with adverse outcomes in multiple sclerosis (MS), but whether its influence on disability progression differs according to immunogenetic background remains unclear. We investigated whether associations between obesity at diagnosis and subsequent disability progression vary by HLA-A*02:01 sta...

Jie Guo, Jing Wu, Tomas Olsson et al. · 0 citations
Open access Sep 2026

Family history of multiple sclerosis and long-term outcomes

Family history is a well-established risk factor for multiple sclerosis (MS), but its influence on disease progression remains unclear. We investigated whether familial MS, including degree of relatedness, is associated with baseline characteristics and disease outcomes. We included individuals with incident MS from th...

A. Hedström, Tomas Olsson, L. Alfredsson · 0 citations
Open access Aug 2026

Shared etiology of late- and adult-onset multiple sclerosis.

Most MS risk factors, including MS heredity, HLA-DRB1*15:01, Epstein-Barr nuclear antigen levels, smoking, and low sun exposure, were associated with both onset groups, with stronger effects in AOMS.

V. Karrenbauer, Tomas Olsson, L. Alfredsson et al. · 0 citations

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