The data indicate that the tumor microenvironment induces Blimp-1 in immunosuppressive Treg and CD8+ T effector cells, thereby limiting the therapeutic efficacy of anti-tumor immune responses.
S. Finotto, M. Chiriac, Susanne Krammer et al.· Journal of Immunology· 0 citations
A multi-population meta-analysis of genome-wide association studies, including 32,470 individuals with and 1,753,462 without bladder cancer, identifies 70 independent risk loci, of which 43 are novel, and uses experimental approaches to uncover how inherited variation influences this risk in the context of smoking.
L. Prokunina-Olsson, O. Flórez-Vargas, Michael G. Levin et al.· Nature Communications· 0 citations
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