Author

A. Hartebrodt

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Open access Oct 2026

Concurrent de novo inference of cell types and gene regulatory networks with NetMap

NetMap is presented, a pipeline that jointly infers cell-level GRNs and clusters cells based on shared regulatory programs, combining state-of-the-art single-cell autoencoders and explainable artificial intelligence methods that outperforms existing methods on synthetic data with a known ground-truth GRN and is able to...

A. Hartebrodt, Mhaned Oubounyt, G. D. de Almeida et al. · bioRxiv · 0 citations

Open access Nov 2025

SignifiKANTE: efficient P-value computation for gene regulatory networks

SignifiKANTE employs gene clustering based on the 1-Wasserstein distance to create a small, constant number of background distributions which enables the simultaneous computation of approximate empirical P-values for multiple target genes, which reduces runtime by orders of magnitudes.

F. Woller, Paul Martini, Souptik Sen et al. · bioRxiv · 1 citation