Author

A. H. Jonsson

2 papers indexed here

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Open access Oct 2026

Accurate and well-powered case-control analysis of spatial molecular data.

As spatial molecular data grow in scope, there is a pressing need to identify disease-associated spatial structures. Current approaches typically make restrictive assumptions such as representing tissue regions by abundances of discrete cell types and samples by abundances of discrete niches; this risks overlooking imp...

Yakir A. Reshef, Lakshay Sood, Michelle Curtis et al. · Nature Methods · 0 citations

Open access Sep 2026

Extraintestinal Reprogramming of Colon-Derived CD4+ Intraepithelial Lymphocytes Reveals a Mechanism Underlying the Gut-Joint Axis.

OBJECTIVE The gut-joint axis is a central paradigm in spondyloarthritis, yet the cellular mechanisms linking intestinal and joint immunity remain poorly understood. One potential link is TCRαβ+ CD4+ intraepithelial lymphocytes in the colon (cIELs) that can traffic to extraintestinal tissues, including the joint. Within...

S. M. Danielson, Connor Eck, Su-Cai Liu et al. · Arthritis & Rheumatology · 0 citations