Open access
Aug 2026
Deletion Analysis of Phase Separation, Amyloid Formation and Prion Propagation by the Intrinsically Disordered Region of Yeast Sup35 Protein
Deletion analysis demonstrates that the N-proximal prion domain (Sup35N) of Sup35 is sufficient for chaperone-dependent prion propagation and that various regions of this domain show differential impacts on LLPS, amyloid aggregation, and prion inheritance.
A. Grizel, Natalia A. Gorsheneva, Ismat Jahan Anee et al.
· International Journal of Mol... · 0 citations