528. Alterations of the event-related potential parameter P300 in antidepressant vagus nerve stimulation: preliminary results of a longitudinal prospective study
Abstract Background Major depressive disorder (MMD) is one of the leading causes of global disease burden worldwide. Around 40 percent of patients suffering from MDD are considered treatment resistant and about 10% have chronic depression who do not achieve remission for years. Vagus nerve stimulation (VNS) is an invas...