A. Gambineri

Diagnosis and management of polycystic ovary syndrome/polyendocrine metabolic ovarian syndrome: unmet needs and areas of clinical confidence among European endocrinologists.

Body mass index outperforms the Rotterdam criteria in defining phenotypic heterogeneity in polycystic ovary syndrome: a multicenter study from the Italian PCOS registry (PCOSOUTCOME.net)

In this multicenter cohort, Rotterdam phenotypes failed to discriminate metabolic risk, whereas BMI-based stratification proved more informative in identifying cardiometabolic complications.

EP637 - ECE_1605 - Body mass index and waist-to-hip ratio patterns in women with and without polycystic ovary syndrome: evidence from an unselected population

In unselected populations, the majority of women with PCOS exhibit a normal BMI, in contrast to clinic-based cohorts, where obesity is markedly overrepresented, which indicates that longitudinal, population-based studies integrating multi-omic data are essential for unraveling BMI-related heterogeneity.

The risk of nephrotic range proteinuria and kidney failure in primary laminopathies is genotype specific

While patients with Lamin A/C Arg482 missense changes are at very low risk for progressive CKD, patients harboring Arg349Trp show nephrotic range proteinuria and kidney failure in midlife, and patients with the Arg349Trp substitution require early renoprotective intervention to potentially halt progression and prevent...