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Open access Sep 2026

Phage heteroresistance in clinical Klebsiella pneumoniae isolates: impact of differentiated capsule expression on phage efficacy

Heteroresistance, commonly described in the context of antibiotics, refers to the presence of resistant subpopulations within a bacterial strain, and is recognized as a likely contributor to treatment failure. Whether population heterogeneity affects phage activity remains poorly understood. We investigated whether...

I. Najjar, Mélanie Roch, Jôiciglecia Pereira dos Santos et al. · 0 citations
Open access Aug 2026

Mapping the resistance landscape: A large-scale study of polymyxin-resistant pathogens circulating in low-and middle-income countries

The increasing prevalence of antimicrobial resistance is a major public health challenge, particularly in low- and middle-income countries (LMICs). Polymyxins are last-resort antibiotics used for treating highly drug-resistant infections, however, the rise of polymyxin-resistant bacterial strains is further reducing tr...

T. Duarte, Holly Floyd, V. Thamlikitkul et al. · 0 citations

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