Comparative Analysis of Plasma Biomarkers of Alzheimer’s Disease and Frontotemporal Dementia: The Dual Role of Soluble Fractalkine as a Biomarker of Frontotemporal Dementia and Its Neuroprotective Effects in Cortical Neurons “In Vitro”
This is the first study showing that increased plasma levels of CX3CR1 and soluble fractalkine could be associated with FTD pathology as compared to control subjects (without neurodegeneration), and the findings suggest that fractalkine mitigates LPS-induced neuronal injury by limiting apoptosis and inflammatory respon...