Purpose Immunotherapy with chemotherapy significantly improves progression-free survival in advanced endometrial cancer (EC), especially in microsatellite instability-high (MSI-H) cases. Despite this, for recurrent EC in the postimmunotherapy setting, new treatment options are urgently needed. The PI3K pathway is frequ...
A. Passarelli, G. L. Scaglione, D. Califano et al.· JCO Precision Oncology· 0 citations
BACKGROUND
Pelvic organ prolapse (POP) frequently coexists with overactive bladder (OAB) symptoms, yet the impact of surgical correction on OAB outcomes remains incompletely characterized across different surgical approaches.
OBJECTIVES
To quantify OAB symptom resolution rates following POP surgery, compare outcomes...
L. Vacca, D. Caramazza, M. Pierro et al.· Neurourology and Urodynamics· 0 citations
Simple Summary The present paper reviews the 2023 FIGO staging system for endometrial cancer, which for the first time incorporates molecular testing (like POLE mutations and p53 status) alongside traditional anatomical findings. This update reflects tumor biology and helps avoid over- or under-treating patients, thoug...
Angela Santoro, G. Angelico, A. d'Amati et al.· Cancers· 0 citations
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