Author

A. F. Hassanabad

2 papers indexed here

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Review Open access Sep 2026

Left Atrial Appendage Occlusion vs Direct Oral Anticoagulants for Atrial Fibrillation

Background Left atrial appendage occlusion (LAAO) is a treatment option to prevent thromboembolic events in patients with atrial fibrillation. However, it remains unclear whether LAAO offers superior efficacy and safety compared with oral anticoagulation for these patients. Objectives This study aimed to assess the eff...

Yuriko Hiruma, T. Aikawa, Iwanari Kawamura et al. · JACC: Advances · 0 citations

Open access Sep 2026

BET inhibitor apabetalone suppresses the fibrotic activation of cardiac fibroblasts associated with heart dysfunction.

BACKGROUND Accumulation of extracellular matrix (ECM) causes tissue fibrosis that contributes to myocardial dysfunction and heart failure (HF), yet there are no approved anti-fibrotic therapeutics that target it. Inhibitors of BET proteins (BETi) reduced fibrosis in preclinical HF models, and clinical-stage BETi, apabe...

S. Wasiak, D. Gilham, L. Fu et al. · Biomedicine & pharmacotherap... · 0 citations