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A. Esmail

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Review Open access Aug 2026

Next-Generation Immune Checkpoint Inhibitors in Gastrointestinal Cancers: Mechanisms, Resistance, and Emerging Therapeutic Strategies

This review explains how cancer cells bypass standard therapies and highlights next-generation immune targets currently being developed to overcome resistance, and examines how combining new immune-boosting drugs with traditional treatments like chemotherapy, radiation, and novel targeted therapies can weaken cancer defenses.

Mariam Ismail, Zaid Alabed, Khaled Alhallaq et al. · 0 citations

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