Author

A. Elshamy

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Oct 2026

Neuroprotective Effects of Bauhinia variegata Flower Extract against D-Galactose-Induced Age-Related Cognitive Impairment: Modulation of the Oxidative Stress-endoplasmic reticulum Axis.

ETHNOPHARMACOLOGICAL RELEVANCE Bauhinia variegata is widely used in traditional medicine for the management of disorders associated with inflammation, oxidative stress, and nervous system dysfunction. The presence of flavonoids and phenolics supports its ethnopharmacological relevance to cognitive impairment, both repo...

Naglaa M. Ammar, Zeinab A. El-Gendy, Asmaa S. Abd Elkarim et al. · Journal of Ethnopharmacology · 0 citations

Oct 2026

Polyphenol-rich Salsola imbericata extract attenuates experimental lung injury via modulating oxidative stress, NLRP3 inflammasome activation and apoptosis singling.

Salsola imbericata is a halophytic plant with promising yet underexplored pharmacological potential. The present study aimed to characterize the metabolite profile of its ethanolic extract (SI-EtOH) and evaluate its protective effects against experimentally induced lung injury. UPLC-PDA-ESI-TOF-MS/MS-based metabolomics...

Asmaa S. Abd Elkarim, Rania F. Ahmed, I. Younis et al. · Tissue & Cell · 0 citations

Aug 2026

Alogliptin mitigates doxorubicin-induced cardiotoxicity in rats: Implications of SIRT3/NRF2 pathway and miRNA-133a.

Present results proved the prophylactic ALO antioxidant, anti-inflammatory, anti-apoptotic, and anti-fibrotic influence on the DOX-induced cardiotoxicity with proposed mechanisms entailing the activation of SIRT3 pathway that may be governed by miRNA-133a.

N. F. Elmongy, Mohamed Ali Abbas, S. Elshora et al. · Tissue & Cell · 0 citations

Open access Aug 2026

Guazuma ulmifolia butanol extract protects against cadmium-induced hepatotoxicity via HO-1/Sirt-1 activation, miRNA–lncRNA modulation, and metabolic reprogramming

Gul-BuOH affords dose-dependent protection against Cd-induced liver injury by modulating oxidative stress, inflammation, metal detoxification, and metabolic pathways, supporting the traditional use of G. ulmifolia and its potential as a multi-target hepatoprotective agent.

O. A. Elsabagh, Abdelbaset M. Elgamal, Heba A. Hassan et al. · PLoS ONE · 0 citations