Aug 2026
Dual knockdown of Scn1b and Gsdmd induces an M2-like functional state in macrophages and modulates inflammation and fibrosis in a rat model of acute respiratory distress syndrome
The potential use of adoptive transfer of siRNA-modified macrophages to influence the progression of ARDS is investigated and dual knockdown of Scn1b and Gsdmd leads to the formation of an M2-like macrophage phenotype in vitro.
Victoria V. Kiseleva, P. Vishnyakova, Anna Kosyreva et al.
· Molecular Biology Reports · 0 citations