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Author

A. Dziergowska

2 papers indexed here

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Open access Aug 2026

The Wobble Uridine tRNA Writer MnmA Shapes Codon-Dependent Stress Response Systems

Escherichia coli uses wobble uridine (U34) modifications to tune codon decoding, but how individual tRNA writer enzymes shape gene expression remains unclear. Here, we identify MnmA, the U34 thiolation enzyme for tRNALys, tRNAGln, and tRNAGlu, as a central regulator linking codon-directed translation to regulon control...

H. Omeoga, Dylan J. Ehrbar, Chetna Mathur et al. · 0 citations
Open access Aug 2026

Growth-dependent tRNA reprogramming and codon bias link translation to metabolic state in Enterococcus faecalis

ABSTRACT Enterococcus faecalis is a gram-positive commensal bacterium of the human gut microbiome and an opportunistic pathogen responsible for many hospital-acquired infections. Despite the clinical importance of E. faecalis, how gene and protein expression are coordinated with growth remains poorly defined. Here, we...

M. M. Mitchener, Caleb M. Anderson, Mark Veleba et al. · 0 citations

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