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Author

A. de Luca

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Open access Oct 2026

Reduced structural connectivity in age-related hearing loss aligns with the sensory deprivation theory.

Age-related hearing loss (ARHL) may contribute to cognitive decline through structural degeneration and brain reorganization, as posited by the sensory deprivation theory. These processes can be characterized by topological changes, such as strengthening and weakening of structural connections between brain regions. St...

J. H. C. Boons, A. de Luca, G. Dingemanse et al. · 0 citations
Open access Oct 2026

Location matters: Attributing cognitive symptoms to white matter hyperintensities in 3,481 memory clinic patients.

BACKGROUND AND AIM In memory clinic patients, assessing diagnostic relevance of white matter hyperintensities (WMHs), as a marker to explain cognitive deficits, can be challenging. Here, we aimed to quantify this relevance by measuring the variance in cognitive function they explain, and consider, beyond total WMH volu...

Ewoud J. van der Lelij, Mirthe Coenen, F. de Kort et al. · 1 citation

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