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Open access Jan 2026

Cholangitis, Choledocholithiasis and a Cholecystocolonic Fistula: A Case Report on a Rare Triple Surgical Challenge

Cholecystocolonic fistula (CCF) is an uncommon complication of gallstone disease and is usually diagnosed intraoperatively. Concomitant choledocholithiasis and acute cholangitis create competing priorities: urgent biliary drainage and definitive treatment of the fistula. A 78‐year‐old woman presented with 3 days of upp...

K. Jaffry, Anthony Tran, Deep Bhowmik et al. · 0 citations
Review Open access Jul 2026

Large language models enable consensus-level interpretation in metagenomic diagnostics

Abstract Metagenomic sequencing can detect a broad range of pathogens, but interpreting which detections are clinically relevant requires expert adjudication that is difficult to scale and standardize. Here we present diagnostic classifiers that formalize expert adjudication by combining structured decision trees with...

E. Steinig, M. Krysiak, K. Deo et al. · 0 citations

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