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Author

A. Churov

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Review Open access Sep 2026

Modulating the NLRP3/IL-1β Axis in Age-Related Atherosclerosis: Natural Products, Molecular Mechanisms, and Translational Perspectives—A Narrative Review

Atherosclerosis is an age-related immune-metabolic disease in which lipid retention, endothelial dysfunction, innate immune activation, and vascular remodeling interact over decades. In older adults, inflammaging, mitochondrial dysfunction, defective autophagy/mitophagy, and cellular senescence may lower the threshold...

Yelizaveta A. Marakhovskaya, Ksenia A. Eruslanova, O. Maltseva et al. · 0 citations
#protein folding Open access Sep 2026

Age-Associated Plasma Protein Signatures and Proteomic Age Estimation by Data-Independent Acquisition Mass Spectrometry in a Russian Cross-Sectional Cohort

Chronological age can be estimated from molecular profiles; however, predictive accuracy alone does not establish a biologically validated ageing clock. We therefore evaluated whether plasma protein intensities measured by data-independent acquisition mass spectrometry (DIA-MS) support chronological-age estimation in a...

M. Arbatskiy, D. Balandin, S. Novikova et al. · 0 citations
#machine learning Preprint Aug 2026

Diagonal Multi-omics Integration of Heterogeneous Datasets

A novel characteristic of dataset heterogeneity is introduced by employing the norm of the difference between the maximum and minimum points in the classical terms of functional analysis.

Maksim V.Kukushkin, M. Arbatskiy, D. Balandin et al. · 0 citations

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