A. Chari

Spectrally-resolved transfer entropy in resting-state SEEG reveals epileptogenic and non-epileptogenic communication in adults and children with refractory epilepsy

Objective. To characterise directed, frequency-resolved communication between seizure onset zone (SOZ) and non-involved zone (NIZ) regions in resting-state stereo-electroencephalography (SEEG) from adults and children with drug-resistant epilepsy (DRE). Approach. We analysed retrospective SEEG from 21 adults and 18 pae...

Diffusion MRI abnormalities localise the epileptogenic zone in paediatric drug-resistant epilepsy

Neurosurgical management of childhood-onset epilepsy in periventricular nodular heterotopia: A systematic review of effectiveness and outcomes.

Minimally invasive ablation appears effective and safe, while neuromodulation offers palliation where curative treatment is not feasible, and Invasive EEG-guided approaches can achieve seizure freedom in around half of children with PVNH-related epilepsy, with outcomes strongly predicted by laterality.

Opposing associations of default mode network and subcortical network efficiency with IQ in children with drug-resistant epilepsy.

Exploratory mediation analyses suggested that opposing DMN and Subcortical Network effects partially accounted for the observed group difference in IQ, highlighting opposing regional, rather than global, network alterations as candidate correlates of IQ variability in paediatric DRE.