Author

A. Cavazza

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Open access

Virus-Like Particles as a Nonviral CRISPR/Cas Editing Delivery Tool.

A protocol for generating VSV-G-pseudotyped VLPs that deliver CRISPR/Cas9 RNPs and their functional validation in surrogate cell lines is described and their functional validation in surrogate cell lines is validated.

Antonio Carusillo, A. Naseem, A. Cavazza · Methods in molecular biology · 0 citations

Open access Jul 2026

In-depth characterization of stem cell potency and genotoxicity for clinical-scale ex vivo CRISPR-Cas9 gene editing

A clinical-compatible platform enabling large-scale manufacturing while preserving HSPC viability, stemness, and multilineage functionality is established and a robust and adaptable roadmap for future HDR-based gene editing platforms is offered.

A. Naseem, W. Vetharoy, T. E. Whittaker et al. · Molecular therapy. Advances · 1 citation