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A. Cao

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Open access Oct 2026

VCP‐Regulated LMF2 Stabilizes the Cholesterol Biosynthesis Enzyme HMGCS1 to Drive Cancer Progression and Confer Capecitabine Resistance in Triple‐Negative Breast Cancer

ABSTRACT Triple‐negative breast cancer (TNBC) is the most therapeutically challenging breast cancer subtype owing to its aggressive nature and lack of effective targeted therapies. Here, we identify lipase maturation factor 2 (LMF2), a previously uncharacterized gene in human cancer, as a novel oncogenic driver that pr...

Qian Zhao, Lisa Andriani, Yin-Ling Zhang et al. · 0 citations

Influence of a family history of breast and/or ovarian cancer on breast cancer outcomes

The results found that women diagnosed with FBC had an early onset of disease in the population studied, and the poor outcome of patients with a family history of BOC associated with survival was restricted to the hormone receptor-positive population.

A. Cao, Min He, G. Di et al. · 0 citations

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