Author

A. Busia

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Open access Jul 2026

Activity and specificity trade-offs in adenine base editors

This work found that the ABEs were fully described by the single dimension of intrinsic deaminase activity with no evidence for independent specialization with respect to local sequence context, editing window width, RNA editing, RNA editing, or genotoxicity.

Maria Lukarska, L. Oltrogge, Hunter M. Nisonoff et al. · bioRxiv · 1 citation