Alterations in Innate Immune Cells During the Progression of Systemic Autoimmune Rheumatic Diseases
Systemic autoimmune rheumatic diseases (SARD) exhibit a prolonged pre-clinical phase during which they have anti-nuclear antibodies (ANAs).[1] However, ANAs cannot be reliably used to predict impending disease because a subset of healthy women are ANA+ (~20%) and the majority of these individuals will not progress...