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Author

A. Binsaleh

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Oct 2026

Integrating in vitro and in silico correlation of thiazole-based carboxamide derivatives as promising SARS-CoV-2 papain-like protease inhibitors: a versatile approach for COVID-19 therapy

Abstract A new series of thiazole-based carboxamide derivatives (5–12) was designed, synthesized with structural elucidation performed using standard spectroscopic techniques including NMR and HRMS. The synthesized compounds were evaluated for their inhibitory activity against SARS-CoV-2 papain-like protease (PLpro) an...

Imran Khan, Rafaqat Hussain, Hina Sarfraz et al. · 0 citations
Sep 2026

Real-world pharmacogenomics-guided antihypertensive treatment response in clinical practice underrepresented population: implications for precision prescribing and medication safety

This retrospective cohort study analyzed 1,247 hypertensive patients treated at Kuwait Teaching Hospital (KTH), Peshawar, between January 2023 and August 2025 to evaluate associations between pharmacogenomics variants and antihypertensive therapy response using electronic health record (EHR) data from Khyber Pakhtunkhw...

Nawal Alsubaie, Muhammad Ilyas, Z. A. Shah et al. · 0 citations
Aug 2026

Thymol dietary supplementation mitigates microplastic-induced hematological disturbances, oxidative stress, immunosuppression, gene dysregulation, and histopathological alterations in Nile tilapia.

Thymol supplementation against polystyrene microplastics exposure in Nile tilapia may be considered a helpful nutritional additive for lessening the negative impacts of PS-MPs.

Badriyah S. Alotaibi, Amany Abdel-Rahman Mohamed, Tarek Khamis et al. · 0 citations

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